V.P. Kukhar Institute
of Bioorganic
chemistry and
Petrochemistry
NAS of Ukraine

Collective monograph “Bioactive compounds, new substances and materials – 2025”

Bioactive compounds, new substances and materials – 2025. Edited by A.O. Kolodyazhna. V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine. Kyiv : LLC “SPE “Interservice”, 2025. 378 p.

https://doi.org/

Title: Bioactive compounds, new substances and materials – 2025

Author(s): Savchuk T.V., Shablykin O.V., Shulga Yu.V. and others

Editor: Kolodyazhna A.O.

Year: 2025

ISBN: 978-966-999-557-5

Publisher: V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine

Place Published: Kyiv

Publication Languages: Ukrainian, English

UDC 54-414, 543.4, 544.4, 547.47, 547.7, 633/635, 661.1, 678.02 

Abstract

The collective monograph presents the works of the employees of the V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine, as well as scientists from other institutes and universities. Two chapters of the book contain scientific works on bioorganic chemistry, organic chemistry, petrochemistry, chemistry of high-molecular compounds, etc. The first part presents the results of the synthesis of new organic compounds, the study of their reactivity, the prediction of pharmacokinetic parameters, the study of biological activity, and the establishment of the relationship between structure and activity. The second chapter introduces scientific developments related to new polymer compositions for various purposes with improved target characteristics, adhesive materials for multi-purpose use with a wide temperature range, pollutant sorbents, new fuels and lubricants, catalysts for oleochemical transformations, and methods for processing anthropogenic waste. The book is intended for a wide range of specialists in the field of chemistry and biology, as well as graduate students and students.

Recommended for publication by the Academic Council of the V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine (protocol No. 12 dated August 28, 2025).

Keywords: organic chemistry, bioorganic chemistry, synthesis, bioactive compounds

Reviewers:

Doctor of Medical Sciences V.V. Zhirnov

Doctor of Chemical Sciences, Professor V.D. Romanenko

References:

1. Kulinkovich O.G. Cyclopropanes in Organic Synthesis. John Wiley & Sons, Inc., 2015. 418 p. DOI:10.1002/9781118978429
2. Neouchy Z., Hullaert J., Verhoeven J. Synthesis of cyclopropyl pinacol boronic esters from dibromocyclopropanes. Synlett. 2022. Vol. 33, N 8. P. 759–766. DOI: 10.1055/s-0037-1610794
3. Teiichi A., Takashi I., Eiichi O., Hiroki S. Reduction of 1-substituted 7-chloro-7-fluoronorcaranes with tributyltin hydride. Journal of Organic Chemistry. 1981. Vol. 46, N 22. P. 4446–4450. DOI: 10.1021/jo00335a024
4. Renslo A., Jaishankar P., Venkatachalam R., Hackbarth C., Lopez S., Patel D.V., Gordeev M. Conformational constraint in oxazolidinone antibacterials. Synthesis and structure-activity studies of (azabicyclo[3.1.0]hexylphenyl) oxazolidinones. Journal of Medicinal Chemistry. 2005. Vol. 48, N 15. P. 5009–5024. DOI: 10.1021/jm058204j
5. Poteat C.M., Jang Y., Jung M., Johnson J.D., Williams R.G., Lindsay V.N.G. Enantioselective synthesis of cyclopropanone equivalents and application to the formation of chiral β‐lactams. Angewandte Chemie – International Edition. 2020. Vol. 59, N 42. P. 18655–18661. DOI: 10.1002/anie.202006786

Collective monograph download link (pdf)